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KMID : 0644319950010010213
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Journal of Korean Oriental Oncology
1995 Volume.1 No. 1 p.213 ~ p.230
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Studies on the Effect of Guichoolpajing-Tang and Gamiguichoolpajing-Tang
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宋錫鎬/Song, Seog Ho
宋炳基/李京燮/Song, Byoung Key/Lee, Kyoung Sup
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Abstract
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The present work was done to investigate the pharmacological effectiveness of Guichoolpajing-Tang and Gamiguichoolpajing-Tang. The extracted water of those two prescription were administered to experimintal animals and determined analgesic, anti-pyretic, anti-inflammatory effects and effects on intravascular coagulation, spontaneous morements of the isolated rat uterus, the uterine contracion induced by oxytocin or PGF_2●, lifespan of mice implanted intraperitoneally with Sarcoma 180. The following results were obtained.
1) The extracted water of Guichoolpjing-Tang and Gamiguichoolpajing-Tang were revealed significant analgesic effect.
2) The extracted water of Guichoolpajing-Tang and Gamiguichoolpajing-tang showed antipyretic effect.
3) The extracted water of Guichoolpajing-tang and Gamiguichoolpajing-Tang showed antiinfiammatory effect. especially, the extracted water of Gamiguichoolpajing-Tang showed more significant dffect than another.
4) concerning the degree of concentration of FDP, Gamiguichoolpjing-Tang treated groups tevealed significant decreases.
5) The extracted water of both prescriptions revealed uterus relaxation on the spontaneous movement of the isolated rat uterus and showed uterine contraction induced by oxytocin or PDF_2●, Especially Guichoolpajing-Tang showed more significant effect than another.
6) The extracted water of both prescriptior both prescriptions showed effect on lifespan of mice implanted intraperitoneally with Sarcoma 180.
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KEYWORD
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